ea0092ps3-30-01 | Thyroid Physiology in Periphery & Development Basic | ETA2023
Dierichs Nathalie
, Meima Marcel
, Edward Visser W.
, Piersma Aldert
, Hessel Ellen
, Peeters Robin
Background: Over the last few decades, in vivo animal experiments have been the gold standard for the assessment of safety of chemicals and pharmaceuticals for human health. However, in vivo animal data has limited relevance for toxicity prediction in humans, especially considering species-specific issues of age, sex and exposure in different life-stages. Within the Virtual Human Platform for Safety Assessment (VHP4Safety) project we aim to develop an animal-...